Which airlines allow a 22 × 16 × 10 in carry-on?

It fits the carry-on limit on 7 of 28 airlines: Southwest, Frontier, Allegiant, Sun Country, easyJet (right at the limit), British Airways and Jet2 (right at the limit). It’s too big for American (1.8 in too wide), Delta (3 in over the total), United (2 in too wide), JetBlue (2 in too wide), Alaska (3 in over the total), Hawaiian (3 in over the total), Breeze (2 in too wide), Avelo (2 in too wide), Ryanair (2.1 in too deep), Wizz Air (0.9 in too deep), AirAsia (1.8 in too wide), Malaysia Airlines (2.7 in over the total), Batik Air (2.7 in over the total), Singapore Airlines (2.7 in over the total), Scoot (2.7 in over the total), Cathay Pacific (1.8 in too wide), Air Canada (0.9 in too deep), WestJet (1.8 in too wide), Jetstar (1.8 in too wide), Qantas (1.8 in too wide) and Virgin Australia (1.8 in too wide).

No: it’s bigger than every published under-seat limit, the largest being 48 × 34 × 23 cm on Qantas. It has to go in the overhead bin.

Free in every fare on Southwest, British Airways and Jet2. On Frontier, Allegiant, Sun Country and easyJet it’s a paid cabin bag: only a smaller under-seat bag is free. On Delta, Alaska, Hawaiian, Batik Air, Cathay Pacific and Jetstar it’s over the carry-on limit and no under-seat size is published, so it’s free only if it fits under the seat in front of you. On American, United, JetBlue, Breeze, Avelo, Ryanair, Wizz Air, AirAsia, Malaysia Airlines, Singapore Airlines, Scoot, Air Canada, WestJet, Qantas and Virgin Australia it’s too big for the cabin and would have to be checked.